通过铟111肌球蛋白特异性显像检测到的阿霉素心脏毒性。
Doxorubicin cardiotoxicity detected by indium 111 myosin-specific imaging.
作者信息
Lekakis J, Vassilopoulos N, Psichoyiou H, Athanassiadis P, Gerali S, Kostamis P, Moulopoulos S
机构信息
Department of Clinical Therapeutics, Athens University, Greece.
出版信息
Eur J Nucl Med. 1991;18(3):225-6. doi: 10.1007/BF02262734.
PMID:1645666
Abstract
A patient with primary hepatoma, treated with doxorubicin and presenting with atypical electrocardiographic findings, was investigated with myosin-specific monoclonal antibody radiolabelled with indium-111. Despite a normal ejection fraction, myosin-specific scintigraphy was positive, indicating doxorubicin cardiotoxicity.
摘要
一名原发性肝癌患者接受阿霉素治疗后出现非典型心电图表现，用铟-111标记的肌球蛋白特异性单克隆抗体进行了研究。尽管射血分数正常，但肌球蛋白特异性闪烁扫描呈阳性，提示阿霉素心脏毒性。
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