Takahashi Y
Department of Neuropharmacology, Brain Research Institute, Niigata City, Japan.
Nihon Yakurigaku Zasshi. 1991 Mar;97(3):135-44. doi: 10.1254/fpj.97.3_135.
There are some functionally important proteins in the central nervous system. We have studied some of these proteins and analyzed the structure and function of their genes and mRNAs. In this review, we briefly described the present state of the studies on 14-3-3 protein, GABA receptor and dopamine receptor from the standpoint of cDNA and genomic DNA analyses. Particularly, we have emphasized the function, heterogeneity, primary structures, nucleotide sequences, gene structures and the distribution of these proteins and mRNAs in the central nervous system.
中枢神经系统中存在一些功能重要的蛋白质。我们已经研究了其中一些蛋白质,并分析了它们的基因和信使核糖核酸的结构与功能。在这篇综述中,我们从互补脱氧核糖核酸和基因组脱氧核糖核酸分析的角度,简要描述了14-3-3蛋白、γ-氨基丁酸受体和多巴胺受体的研究现状。特别是,我们着重介绍了这些蛋白质和信使核糖核酸在中枢神经系统中的功能、异质性、一级结构、核苷酸序列、基因结构及分布。