有丝分裂染色体的结构-功能模型。

Structural-functional model of the mitotic chromosome.

作者信息

Polyakov V Yu, Zatsepina O V, Kireev I I, Prusov A N, Fais D I, Sheval E V, Koblyakova Yu V, Golyshev S A, Chentsov Yu S

机构信息

Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia.

出版信息

Biochemistry (Mosc). 2006 Jan;71(1):1-9. doi: 10.1134/s0006297906010019.

DOI:10.1134/s0006297906010019

PMID:16457612

Abstract

In the present review the structural role of noncoding DNA, mechanisms of differential staining of mitotic chromosomes, and structural organization of different levels of DNA compactization are discussed. A structural-functional model of the mitotic chromosome is proposed based on the principle of discreteness of structural levels of DNA compactization.

摘要

在本综述中，讨论了非编码DNA的结构作用、有丝分裂染色体的差异染色机制以及DNA压缩不同水平的结构组织。基于DNA压缩结构水平的离散性原理，提出了有丝分裂染色体的结构功能模型。