Quyyumi Arshed A
Emory University School of Medicine, Atlanta, Georgia 30322, USA.
J Am Coll Cardiol. 2006 Feb 7;47(3 Suppl):S66-71. doi: 10.1016/j.jacc.2004.11.075.
The current review highlights gender-specific issues in ischemic heart disease (IHD) presentation, evaluation, and outcomes with a special focus on the results derived from the National Institutes of Health-National Heart, Lung, and Blood Institute-sponsored Women's Ischemia Syndrome Evaluation (WISE) study. New evidence on gender-based differences in vascular wall, atherosclerotic plaque deposition, pathophysiology, and innovative cardiovascular imaging techniques are reviewed. Critical areas of further inquiry needed to advance new gender-specific IHD understanding are detailed.
本综述重点介绍了缺血性心脏病(IHD)在临床表现、评估和治疗结果方面的性别特异性问题,特别关注美国国立卫生研究院-国立心肺血液研究所资助的女性缺血综合征评估(WISE)研究的结果。文中回顾了血管壁、动脉粥样硬化斑块沉积、病理生理学以及创新性心血管成像技术等方面基于性别的差异的新证据。详细阐述了推进对IHD性别特异性新认识所需进一步探究的关键领域。