智能眼罩治疗干眼症的临床评估

Clinical evaluation of the Smart Plug in the treatment of dry eyes.

作者信息

Kojima Takashi, Dogru Murat, Ishida Reiko, Goto Eiki, Matsumoto Yukihiro, Tsubota Kazuo

机构信息

Department of Ophthalmology, Keio University, Tokyo, Japan.

出版信息

Am J Ophthalmol. 2006 Feb;141(2):386-8. doi: 10.1016/j.ajo.2005.08.032.

DOI:10.1016/j.ajo.2005.08.032

PMID:16458703

Abstract

PURPOSE

To evaluate the efficacy of a thermo sensitive punctum plug, the Smart Plug, in the treatment of dry eyes.

DESIGN

Observational case-series study.

METHODS

Eighteen eyes of 10 dry eye patients who previously failed conventional plug insertion were enrolled. Schirmer 1 test, vital staining scores, and tear clearance tests were performed before plug insertion, at 2 weeks, 1 month, and 3 months after insertion.

RESULTS

Although Schirmer test values were not significantly different before and after plug insertion, the tear clearance rate considerably decreased (Before insertion: 14.8+/-11.4; After insertion: 8.2+/-6.6) (P<.05). Rose-Bengal and fluorescein scores improved significantly after plug insertion (Rose-Bengal: Before insertion: 6.4+/-2.0; After insertion: 3.3+/-1.6 points, Fluorescein: Before insertion: 4.8+/-2.3; After insertion: 2.1+/-1.3) (P<.05). No complications were observed.

CONCLUSIONS

Smart Plug proved to be a safe and efficient option in the treatment of dry eye.

摘要

目的

评估热敏泪小点塞（智能塞）治疗干眼症的疗效。

设计

观察性病例系列研究。

方法

纳入10例曾行传统泪小点塞植入术失败的干眼症患者的18只眼。在植入泪小点塞前、植入后2周、1个月和3个月进行泪液分泌试验、活体染色评分和泪液清除试验。

结果

虽然植入泪小点塞前后泪液分泌试验值无显著差异，但泪液清除率显著降低（植入前：14.8±11.4；植入后：8.2±6.6）（P<0.05）。植入泪小点塞后孟加拉玫瑰红和荧光素评分显著改善（孟加拉玫瑰红：植入前：6.4±2.0；植入后：3.3±1.6分，荧光素：植入前：4.8±2.3；植入后：2.1±1.3）（P<0.05）。未观察到并发症。