Ahmed Ahmed A, Mohamed Abou El-Hamd H, Karchesy Joe, Asakawa Yoshinori
Department of Chemistry, Faculty of Science, El-Minia University, El-Minia 91516, Egypt.
Phytochemistry. 2006 Mar;67(5):424-8. doi: 10.1016/j.phytochem.2005.12.009. Epub 2006 Feb 3.
Salvidorol (1), a irregular nor-abietane-type diterpene, was isolated from the aerial parts of Salvia dorrii, in addition to two epimeric abietane diterpenes (2 and 3). This is the first report of a nor-diterpene with an irregular skeleton. The structures were established by high-field NMR techniques ((1)H-(1)H COSY, DEPT, HMQC, HMBC, NOESY and HRMS) and in case of 2 was confirmed by X-ray analysis.
salvidorol(1)是一种不规则的降枞酸型二萜,从多裂鼠尾草的地上部分分离得到,此外还分离出两种差向异构的枞酸型二萜(2和3)。这是关于具有不规则骨架的降二萜的首次报道。通过高场核磁共振技术(¹H-¹H COSY、DEPT、HMQC、HMBC、NOESY和HRMS)确定了其结构,化合物2的结构通过X射线分析得到证实。