Trounson Alan, Pebay Alice
Monash Immunology and Stem Cell Laboratories, Monash University, Building 75, Clayton, Victoria 3800, Australia.
Dev Cell. 2006 Feb;10(2):158-9. doi: 10.1016/j.devcel.2006.01.007.
Neurotrophins act on embryonic cells through TRK receptors to inhibit apoptosis by phosphorylation of AKT. In a recent paper in Nature Biotechnology, show that the presence of selected neurotrophins enables cloning of trypsinized single embryonic stem cells and potentially increases the availability and usefulness of these stem cells.