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A role for neurotrophins in embryonic stem cell growth.

作者信息

Trounson Alan, Pebay Alice

机构信息

Monash Immunology and Stem Cell Laboratories, Monash University, Building 75, Clayton, Victoria 3800, Australia.

出版信息

Dev Cell. 2006 Feb;10(2):158-9. doi: 10.1016/j.devcel.2006.01.007.

DOI:10.1016/j.devcel.2006.01.007
PMID:16459295
Abstract

Neurotrophins act on embryonic cells through TRK receptors to inhibit apoptosis by phosphorylation of AKT. In a recent paper in Nature Biotechnology, show that the presence of selected neurotrophins enables cloning of trypsinized single embryonic stem cells and potentially increases the availability and usefulness of these stem cells.

摘要

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