黑皮质素途径与能量稳态的分子遗传学
The molecular genetics of the melanocortin pathway and energy homeostasis.
作者信息
Leibel Rudolph L
机构信息
Columbia University, Division of Molecular Genetics and Naomi Berrie Diabetes Center, 1150 St. Nicholas Avenue, Room 620, New York, New York 10032, USA.
出版信息
Cell Metab. 2006 Feb;3(2):79-81. doi: 10.1016/j.cmet.2006.01.010.
PMID:16459307
Abstract
The CNS melanocortin pathway plays an important role in the control of body weight. Two papers in this issue of Cell Metabolism, Lee et al., 2006 and Biebermann et al., 2006, suggest that beta MSH--a product of POMC processing--plays an unanticipated role in this pathway in humans.
摘要
中枢神经系统黑皮质素通路在体重控制中发挥着重要作用。本期《细胞代谢》杂志上的两篇论文，Lee等人于2006年发表的以及Biebermann等人于2006年发表的，表明β促黑素（一种阿黑皮素原加工产物）在人类该通路中发挥着意想不到的作用。
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