Culty Thibaut, Delongchamps Nicolas Barry, Dominique Sebastien, Servin Frederique, Ravery Vincent, Boccon-Gibod Laurent
Department of Urology, Bichat Hospital, Paris, France.
Urology. 2006 Feb;67(2):424.e1-424.e2. doi: 10.1016/j.urology.2005.09.008.
Posterior urethral valves (PUVs) in patients with Down syndrome (DS) have been previously described. However, no case of PUVs has been reported in an adult patient with DS. We report on a 40-year-old man with DS, who presented with two severe urinary infections and obstructive symptoms. He was found to have type 3 PUVs associated with bladder neck sclerosis. PUV resection and bladder neck incision were done. Because PUVs seem to be more frequent in patients with DS, complete investigations should be performed, even in adults with DS, in the case of urinary infection or lower urinary tract symptoms.
先前已有关于唐氏综合征(DS)患者后尿道瓣膜(PUV)的描述。然而,尚未有成年DS患者发生PUV的病例报告。我们报告一例40岁的DS男性患者,该患者出现两次严重的泌尿系统感染及梗阻症状。经检查发现其患有3型PUV并伴有膀胱颈硬化。遂行PUV切除术及膀胱颈切开术。由于DS患者中PUV的发生率似乎更高,因此,即使是成年DS患者,若出现泌尿系统感染或下尿路症状,也应进行全面检查。