Jackson R L, Morrisett J D, Gotto A M, Segrest J P
Mol Cell Biochem. 1975 Jan 31;6(1):43-50. doi: 10.1007/BF01731865.
In this article, we review the current state of knowledge about the structure of human plasma high density lipoproteins. Recent advances in this field, including amino acid sequencing and lipid-binding studies, suggest that the plasma lipoproteins have specific sites with special structural features that account for their ability to bind and transport lipid. A hypothesis which describes the structure of these lipid-binding sites and their interaction with lipid is presented.
