Fox Leanne M, Wingerter Sarah, Ahmed Asim, Arnold Alana, Chou Joseph, Rhein Lawrence, Levy Ofer
Division of Infectious Diseases, Children's Hospital Boston, Harvard Medical School, Boston, MA.
Pediatr Infect Dis J. 2006 Feb;25(2):169-73. doi: 10.1097/01.inf.0000195438.09628.b0.
A case of transfusion-associated neonatal babesiosis is presented. Jaundice, hepatosplenomegaly, anemia and conjugated hyperbilirubinemia developed in this preterm infant. The diagnosis was eventually made by blood smear, serology and polymerase chain reaction. The patient was treated with clindamycin and quinine and made a favorable recovery. Of neonatal babesiosis reported in the literature, 9 other cases are reviewed, including 6 that were transfusion-associated, 2 congenital and 2 tick transmitted.
本文报告了一例输血相关性新生儿巴贝斯虫病病例。该早产儿出现黄疸、肝脾肿大、贫血和结合胆红素血症。最终通过血涂片、血清学和聚合酶链反应确诊。患者接受了克林霉素和奎宁治疗,恢复良好。文中还回顾了文献报道的其他9例新生儿巴贝斯虫病病例,其中6例为输血相关性,2例为先天性,2例为蜱传播。