北美的儿童蜱传感染。
Tick-borne infections in children in North America.
机构信息
Department of Pediatrics, Yale School of Medicine.
Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, Connecticut, USA.
出版信息
Curr Opin Pediatr. 2024 Apr 1;36(2):156-163. doi: 10.1097/MOP.0000000000001326. Epub 2024 Jan 3.
PURPOSE OF REVIEW
Because both incidence and awareness of tick-borne infections is increasing, review of major infections and recent advances related to their diagnosis and management is important.
RECENT FINDINGS
A new algorithm, termed modified two-tier testing, for testing for antibodies to Borrelia burgdorferi , the cause of Lyme disease, has been approved and may replace traditional two-tier testing. In addition, doxycycline is now acceptable to use for treatment of and/or prophylaxis for Lyme disease for up to 21 days in children of any age. Borrelia miyamotoi , a bacterium in the relapsing fever type of Borrelia, is the first of this type of Borrelia that is transmitted by hard-bodied ticks such as Ixodes scapularis.
SUMMARY
Awareness of these infections and advances in their diagnosis and treatment is important to assure the best outcomes for affected patients. Table 1 contains a summary of infections discussed.
目的综述
由于蜱传感染的发病率和知晓率都在上升，因此有必要对主要感染进行综述，并对与这些感染的诊断和治疗相关的最新进展进行讨论。
最新发现
一种新的检测博氏疏螺旋体（引起莱姆病的病原体）抗体的算法，称为改良两阶段检测法，已经获得批准，可能会替代传统的两阶段检测法。此外，多西环素现在可用于治疗和/或预防莱姆病，儿童各年龄段的疗程最长可达 21 天。伯氏疏螺旋体，一种回归热型疏螺旋体，是第一种通过硬壳蜱（如肩突硬蜱）传播的疏螺旋体。
总结
了解这些感染以及在其诊断和治疗方面的最新进展对于确保受感染患者获得最佳结果非常重要。表 1 中包含了讨论的感染的总结。
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