Roy P, Hirasawa T, Fernandez M, Blinov V M, Sanchez-Vixcain Rodrique J M
Department of Environmental Health Sciences, University of Alabama, Birmingham 35294.
J Gen Virol. 1991 Jun;72 ( Pt 6):1237-41. doi: 10.1099/0022-1317-72-6-1237.
The complete sequence of the S7 RNA that codes for the major group-specific coat protein. VP7, of African horsesickness virus serotype 4 (AHSV-4) was determined from cDNA analyses and found to be 1179 nucleotides in length. One single open reading frame of 353 codons was observed defining a protein of Mr 38,107 with a net charge of -1.5 at neutral pH. Comparison of the AHSV-4 VP7 sequence with that of bluetongue virus serotype 10 revealed an overall similarity of 44%, with the amino- and carboxy-terminal regions exhibiting the greatest levels of homology. In addition, potential secondary structures of the terminal sequences of the S7 RNA segments of AHSV-4 and BTV serotypes 10, 13 and 17 are presented.
