Suárez Fernández Guillermo
An R Acad Nac Med (Madr). 2005;122(2):215-28; discussion 228-32.
A review and update about a new zoonosis, as it is the Avian Influenza or "poultry grippe" has been made. This disease is endemic in the Southeast of Asia and continues at present time, being active in Vietnam and Tailand. We have considered the Natural History of the Avian Influenza and specifically the late epidemies, starting from the one in 1997 in Hong Kong, in which an Orthomyxovirus type A, subtype H5N1, broke the interespecies barrier. A health analysis is made, both for the present moment and the future, about the possibility of a World pandemic flu, originated by the mentioned Orthomyxovirus type A, agent of the Avian Influenza of highly virulent specificic virus strain pathogenic for men. The most favourable fact, among others, to deny the possibility of a future pandemic flu is the stability of H5N1 strain in both epidemics of poultry in Hong Kong and in the Southeast of Asia.
关于一种新的人畜共患病——禽流感或“家禽流感”,已有一篇综述及更新内容。这种疾病在亚洲东南部呈地方流行性,目前仍在持续,在越南和泰国较为活跃。我们研究了禽流感的自然史,特别是从1997年香港的那次疫情开始的后期疫情,当时一种甲型正粘病毒,H5N1亚型,突破了种间屏障。针对当前和未来由上述甲型正粘病毒引发全球大流行性流感的可能性进行了健康分析,该病毒是高致病性特定病毒株的禽流感病原体,对人类致病。诸多因素中,最有利的一点是,H5N1毒株在香港及亚洲东南部的两次家禽疫情中都保持稳定,这否定了未来发生大流行性流感的可能性。