Reusch C, Hähnle B
1. Medizinischen Tierklinik, Ludwig-Maximilians-Universität München.
Tierarztl Prax. 1991 Feb;19(1):102-6.
We compared the results of the ACTH stimulation tests with measurements of alkaline phosphatase and serum cholesterol during Lysodren therapy in 23 dogs with pituitary-dependent hyperadrenocorticism. The ACTH stimulation test proved to be a very sensitive parameter, by which the extent of Lysodren under- or overdosage could be reliably estimated. On the other hand, regulation of the individual Lysodren requirement was not possible by measuring AP and serum cholesterol only. However, it is highly probable that those two parameters can be used to evaluate the general state of metabolism, and they appear to be of prognostic value when greatly elevated.
我们比较了23只患有垂体依赖性肾上腺皮质功能亢进的犬在使用米托坦治疗期间促肾上腺皮质激素（ACTH）刺激试验的结果与碱性磷酸酶和血清胆固醇的测量值。ACTH刺激试验被证明是一个非常敏感的参数，通过它可以可靠地估计米托坦的用量不足或过量情况。另一方面，仅通过测量碱性磷酸酶和血清胆固醇无法调节个体对米托坦的需求量。然而，很有可能这两个参数可用于评估代谢的总体状态，并且当它们大幅升高时似乎具有预后价值。
