一例由微小根霉引起的腹膜炎病例。

A case of peritonitis caused by Rhizopus microsporus.

作者信息

Monecke Stefan, Hochauf Kristina, Gottschlich Birgit, Ehricht Ralf

出版信息

Mycoses. 2006 Mar;49(2):139-42. doi: 10.1111/j.1439-0507.2006.01190.x.

DOI:10.1111/j.1439-0507.2006.01190.x

Abstract

We report a case of a 62-year-old female patient who developed peritonitis after receiving a renal transplant. Candida glabrata was detected and treated with voriconazole. As the patient did not improve under therapy, laparotomy was performed. Mould-like plaques were found on the peritoneum. Using culture as well as pan-fungal polymerase chain reaction (PCR) followed by DNA microarray hybridisation of the amplicon, the causative agent was identified as Rhizopus microsporus. Despite aggressive surgical treatment, intravenous therapy with amphotericin B and topical administration of Lavasept (polyhexamethylenbiguanide), the patient died.

摘要

我们报告一例62岁女性患者，在接受肾移植后发生腹膜炎。检测到光滑念珠菌并使用伏立康唑进行治疗。由于患者在治疗过程中未见好转，遂行剖腹探查术。在腹膜上发现了霉菌样斑块。通过培养以及泛真菌聚合酶链反应（PCR），随后对扩增子进行DNA微阵列杂交，确定病原体为微小根霉。尽管进行了积极的手术治疗、两性霉素B静脉治疗以及局部应用Lavasept（聚六亚甲基双胍），患者仍死亡。