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冠状动脉狭窄的无创评估。

Noninvasive assessment of coronary stenosis.

作者信息

Silva C, Cheng S, Lima J A C

机构信息

Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

出版信息

Minerva Cardioangiol. 2006 Feb;54(1):41-52.

PMID:16467741
Abstract

Invasive coronary angiography (ICA) has been the gold standard in the diagnosis of coronary artery disease (CAD) for a long time and angiographic procedures performed annually in the United States have steadily increased during the last 25 years. The unmatched temporal and spatial imaging resolution, the high level contrast between the coronary lumen and the adjacent structures, and the ability to concurrently perform percutaneous coronary interventions (PCI) are the technical advantages of coronary angiography. However, the isolated intraluminal imaging, the relatively high financial cost of the procedure, and the risks associated with catheterization may be limitations to its use. Moreover, a better selection of patients really in need of ICA and PCI is necessary since many patients referred for ICA are found not to have significant CAD. Therefore, a remarkable technical progress has been achieved by both cardiac magnetic resonance and cardiac computed tomography in this regard for the noninvasive detection of coronary stenoses.

摘要

长期以来,有创冠状动脉造影(ICA)一直是诊断冠状动脉疾病(CAD)的金标准,在过去25年中,美国每年进行的血管造影手术稳步增加。冠状动脉造影的技术优势在于其无与伦比的时间和空间成像分辨率、冠状动脉管腔与相邻结构之间的高对比度,以及同时进行经皮冠状动脉介入治疗(PCI)的能力。然而,其仅进行管腔内成像、该检查相对较高的经济成本以及与导管插入术相关的风险可能限制其应用。此外,由于许多接受ICA检查的患者被发现没有明显的CAD,因此有必要更好地筛选真正需要ICA和PCI的患者。因此,在无创检测冠状动脉狭窄方面,心脏磁共振成像和心脏计算机断层扫描在这方面都取得了显著的技术进步。

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