Hoffmann L A, Kümpfel T, Heer I, Hohlfeld R
Institut für Klinische Neuroimmunologie, Klinikum der Universität München-Grosshadern, München.
Nervenarzt. 2006 Jun;77(6):663-4, 666-8, 670. doi: 10.1007/s00115-006-2053-7.
Pregnancy and family planning issues are prominent concerns in the medical care of multiple sclerosis patients, since the disease onset often coincides with a period of life that is decisive in this regard. Multiple sclerosis is a chronic disorder with an unpredictable course and is widely treated with long-term immunomodulatory agents, raising questions regarding the complications and effects of these therapies on pregnancy. This paper gives an overview of the relevant literature and provides a basis for individual counselling of this group of multiple sclerosis patients.
妊娠和计划生育问题是多发性硬化症患者医疗护理中的突出关注点,因为疾病发病往往与在这方面具有决定性意义的人生阶段相重合。多发性硬化症是一种病程不可预测的慢性疾病,广泛采用长期免疫调节药物进行治疗,这就引发了关于这些疗法对妊娠的并发症和影响的问题。本文概述了相关文献,并为对这组多发性硬化症患者进行个体化咨询提供了依据。