[毛喉鞘蕊花根的化学成分研究]
[Studies on the chemical constituents in root of Coleus forskohlii].
作者信息
Xu Ling-ling, Lu Jie, Li Wei-jia, Kong Ling-yi
机构信息
Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210038, China.
出版信息
Zhongguo Zhong Yao Za Zhi. 2005 Nov;30(22):1753-5.
OBJECTIVE
To study the chemical constituents in root of Coleusforskohlii.
METHOD
The chemical constituents were isolated by column chromatography. The structures were elucidated on the basis of IR, MS, 1H-NMR, 13C-NMR and 2D-NMR experiments.
RESULT
Six compounds were obtained and the structures were identified as 14-deoxycoleon U (1), demethylcryptojaponol (2), alpha-amyrin (3), betulic acid (4), alpha-cedrol (5) and beta-sitosterol (6).
CONCLUSION
Compounds 1 and 2 were isolated from the genus Coleus for the first time. Compounds 3 and 4 were isolated from C. forskohlii for the first time.
目的
研究毛喉鞘蕊花根中的化学成分。
方法
采用柱色谱法分离化学成分。通过红外光谱（IR）、质谱（MS）、核磁共振氢谱（1H-NMR）、核磁共振碳谱（13C-NMR）和二维核磁共振谱（2D-NMR）实验对结构进行解析。
结果
得到6个化合物，其结构分别鉴定为14-去氧毛喉鞘蕊花素U（1）、去甲基隐丹参醇（2）、α-香树脂醇（3）、桦木酸（4）、α-雪松醇（5）和β-谷甾醇（6）。
结论
化合物1和2首次从鞘蕊花属植物中分离得到。化合物3和4首次从毛喉鞘蕊花中分离得到。
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