Fukushima K, Uchida K
Department of Anesthesiology, School of Medicine, Keio University, Tokyo.
Masui. 1991 Jan;40(1):101-4.
Pancuronium, vecuronium and pipecuronium are quaternary ammonium steroidal neuromuscular blocking agents. These drugs are typical nondepolarizing muscle relaxants. The steroidal compounds and/or their metabolites have been determined using mass spectrometry or gas chromatography. In this review, these analytical methods and application of the methods to pharmacokinetics are introduced.
潘库溴铵、维库溴铵和哌库溴铵是季铵类甾体神经肌肉阻滞剂。这些药物是典型的非去极化型肌肉松弛剂。甾体化合物和/或其代谢产物已通过质谱法或气相色谱法测定。在本综述中，介绍了这些分析方法及其在药代动力学中的应用。
