López-Huertas Eduardo, Teucher Birgit, Boza Julio J, Martínez-Férez Antonio, Majsak-Newman Gosia, Baró Luis, Carrero Juan J, González-Santiago María, Fonollá Juristo, Fairweather-Tait Susan
Institute of Food Research, Norwich, United Kingdom.
Am J Clin Nutr. 2006 Feb;83(2):310-6. doi: 10.1093/ajcn/83.2.310.
Adequate intakes of calcium are required for optimal bone health and protection against chronic disease. Dairy products are an excellent source of calcium.
The absorption of calcium from a range of fortified milks was measured in humans with the use of stable isotopes.
Fifteen volunteers participated in a randomized, controlled, double-blind crossover study. Five types of semi-skimmed (1.9% fat) milk drinks were administered with a light breakfast: standard milk (control milk); milk enriched with calcium from milk solids and tricalcium phosphate [(TCP) MSS milk]; milk enriched with calcium from concentrated milk (CON milk); milk with added fructo-oligosaccharides [(FOSs) FOS milk]; and milk with added caseinophosphopeptides [(CPPs) CPP milk]. All the milks were labeled with 42Ca as CaCl2. The MSS milk was also labeled with 44Ca as TCP. The quantity of calcium in each drink was kept the same by varying the volume given.
Calcium absorption did not differ significantly between the control milk and the calcium-fortified milks (MSS and CON milk) or the FOS and CPP milks. However, calcium absorption from the TCP added to the MSS milk was significantly higher than that from the control milk (27.5 +/- 7.6% and 24.5 +/- 7.3%, respectively; P = 0.003).
Calcium-enriched milks are a valuable source of well-absorbed calcium. Absorption of added calcium as TCP was higher than that of calcium from the control milk, but the addition of FOSs or CPPs did not significantly increase calcium absorption. Further research is needed to ascertain the cost-effectiveness and public health benefits of consuming fortified milks.
充足的钙摄入对于骨骼健康和预防慢性病至关重要。乳制品是钙的优质来源。
利用稳定同位素测定一系列强化牛奶中钙的人体吸收率。
15名志愿者参与了一项随机、对照、双盲交叉研究。五种半脱脂(脂肪含量1.9%)牛奶饮品搭配清淡早餐给予:标准牛奶(对照牛奶);添加了乳固体和磷酸三钙(TCP)来强化钙的牛奶(MSS牛奶);添加了浓缩牛奶来强化钙的牛奶(CON牛奶);添加了低聚果糖(FOS)的牛奶(FOS牛奶);添加了酪蛋白磷酸肽(CPP)的牛奶(CPP牛奶)。所有牛奶均用氯化钙形式的42Ca进行标记。MSS牛奶还用TCP形式的44Ca进行了标记。通过改变给予的体积使每种饮品中的钙含量保持相同。
对照牛奶与强化钙的牛奶(MSS和CON牛奶)或FOS和CPP牛奶之间的钙吸收率无显著差异。然而,添加到MSS牛奶中的TCP的钙吸收率显著高于对照牛奶(分别为27.5±7.6%和24.5±7.3%;P = 0.003)。
强化钙的牛奶是吸收良好的钙的宝贵来源。添加的TCP形式的钙的吸收率高于对照牛奶中的钙,但添加FOS或CPP并未显著提高钙吸收率。需要进一步研究以确定饮用强化牛奶的成本效益和对公众健康的益处。