Haddad Haissam
Curr Opin Cardiol. 2006 Mar;21(2):118-9. doi: 10.1097/01.hco.0000203839.72902.02.
The evolution of scientific advancements that paved the way for clinical cardiac transplantation spans the era of the 20 century, heart transplantation has revolutionized therapy for end-stage heart failure. Demand far exceeds supply, resulting in a long waiting period, and an increasing number of deaths while on a waiting list. The shortage of donors poses dilemmas for allocation of organs and managing the waiting list.
The disparity between the demand and supply for donor hearts makes cardiac retransplantation an ethical issue with some patients being allowed a second transplant while some patients are dying on the waiting list before receiving their first transplant, especially with overall sub-optimal outcomes compared with primary transplantation.
The cardiac transplant community is mandated to closely monitor the results of cardiac retransplantation to identify the appropriate candidate who should receive a retransplantation.
20世纪见证了为临床心脏移植铺平道路的科学进步，心脏移植彻底改变了终末期心力衰竭的治疗方法。需求远远超过供应，导致等待时间漫长，且等待名单上的死亡人数不断增加。供体短缺给器官分配和等待名单管理带来了难题。
供体心脏供需之间的差距使心脏再次移植成为一个伦理问题，一些患者被允许进行二次移植，而一些患者在等待首次移植时就在等待名单上死亡，尤其是与初次移植相比总体结果欠佳。
心脏移植界必须密切监测心脏再次移植的结果，以确定适合接受再次移植的候选人。
