Magazù Salvatore, Migliardo Federica, Telling Mark T F
Dipartimento di Fisica, Università di Messina, P.O. Box 55, I-98166 Messina, Italy. smagazu@.unime.it
J Phys Chem B. 2006 Jan 19;110(2):1020-5. doi: 10.1021/jp0536450.
The present paper shows high-resolution quasi-elastic neutron scattering (QENS) findings on homologues disaccharides (i.e. trehalose, maltose, and sucrose)-water mixtures as a function of temperature. The QENS measurements were performed on both partially deuterated disaccharides in D2O and on hydrogenated disaccharides in H2O to separate the solute dynamics from that of the solvent. The results highlight a noticeable disaccharide kosmotrope character, with results more marked for trehalose. Such evidence accounts for its higher bioprotective effectiveness.
本文展示了关于同系双糖（即海藻糖、麦芽糖和蔗糖）-水混合物随温度变化的高分辨率准弹性中子散射（QENS）研究结果。对D2O中部分氘代双糖以及H2O中氢化双糖进行了QENS测量，以将溶质动力学与溶剂动力学区分开来。结果突出了双糖显著的促溶剂特性，海藻糖的结果更为明显。这些证据解释了其更高的生物保护效力。
