Lobato Muñoz A, Ortiz Reina S, Baquedano Rodríguez J, De la Cruz Mera A, Merino Royo E, Cassinello Ogea C
Servicio de Cirugía General, Hospital Militar Central Gómez Ulla, Madrid.
Rev Esp Enferm Dig. 1991 Apr;79(4):289-93.
We present a case report of Caroli's disease with related cholangiocarcinoma in a 30 years old white woman. The risk of Caroli's disease malignization is estimated about 7-12% being cholangiocarcinoma the histopathologic pattern most frequently found. This frequency, which is over 100 times higher than that expected in the general population, make us think over the possibility of being some premalignant agent, if not a really carcinogenic one in Caroli's disease. The risk of degeneration is proportional to time of evolution of the disease so, when it is possible, the resective surgery should be elected.
我们报告一例30岁白人女性的卡罗里病合并相关胆管癌的病例。卡罗里病恶变的风险估计约为7%-12%，胆管癌是最常见的组织病理学类型。这种发生率比一般人群预期的高出100多倍，这使我们思考卡罗里病中是否存在某种癌前病变因素，即便不是真正的致癌因素。退变风险与疾病进展时间成正比，所以在可能的情况下，应选择根治性手术。
