Domnitskaia T M, Gracheva O A, Korochkina G V, Dadova L V, Sidorenko B A, Nosenko E M
Kardiologiia. 2006;46(1):32-8.
Complex noninvasive investigation of arterial vascular bed and microcirculation of lower extremities was carried out in 87 patients with diabetes and 47 patients with atherosclerosis obliterans of lower extremities without diabetes. Color duplex scanning allowed to detect occlusive-stenotic and nonocclusive changes of arterial vascular bed in patients with type 2 diabetes. Calcinated atherosclerotic plaques in patients with type 2 diabetes more often localize in superficial femoral, popliteal arteries and arteries of the calf. Such plaques are twice as frequent among patients with atherosclerosis obliterans with diabetes compared with those without diabetes. Laser Doppler flowmetry with test of reactive postocclusion hyperemia and positional test in patients with atherosclerosis obliterans and type 2 diabetes allows to reveal more pronounced disturbances of microcirculation compared with patients without diabetes. In patients with type 2 diabetes with hemodynamically insignificant stenoses of arteries of lower extremities laser doppler flowmetry and transcutaneous measurement of oxygen tension in skin of a foot reveal disturbances of microcirculation.
对87例糖尿病患者和47例无糖尿病的下肢动脉硬化闭塞症患者进行了下肢动脉血管床和微循环的复杂无创检查。彩色双功能超声扫描能够检测2型糖尿病患者动脉血管床的闭塞-狭窄性和非闭塞性变化。2型糖尿病患者的钙化动脉粥样硬化斑块更常位于股浅动脉、腘动脉和小腿动脉。与无糖尿病的动脉硬化闭塞症患者相比,合并糖尿病的动脉硬化闭塞症患者中此类斑块的出现频率高出两倍。与无糖尿病患者相比,对动脉硬化闭塞症和2型糖尿病患者进行反应性阻断后充血试验和体位试验的激光多普勒血流仪检查,能发现更明显的微循环障碍。在下肢动脉血流动力学狭窄不明显的2型糖尿病患者中,激光多普勒血流仪检查和经皮测量足部皮肤氧张力可发现微循环障碍。