Podpalov V P, Deev A D, Sivakov V P, Rozum L A
Kardiologiia. 2006;46(1):39-42.
Risk factors and parameters of heart rate variability during active orthoclinostatic test in subjects with normal blood pressure were assessed in a 5 year cohort study on 519 individuals. Logistic stepwise regression revealed most informative factors associated with development of hypertension: sex (p=0.029), body mass index (p=0.005), salt sensitivity threshold (p=0.048), dynamics of heart rate during exercise test (p=0.035). Addition of parameters of heart rate variability (dynamics of standard deviation of R-R intervals and of low frequency component of spectrum during active orthoclinostatic test) increased accuracy of prognosis. With the use of constructed models risk profiles were calculated. Thus, parameters of heart rate variability allow to improve prognostic value of a model.
在一项针对519名个体的为期5年的队列研究中，对血压正常的受试者在主动直立倾斜试验期间心率变异性的危险因素和参数进行了评估。逻辑逐步回归揭示了与高血压发生相关的最具信息量的因素：性别（p=0.029）、体重指数（p=0.005）、盐敏感性阈值（p=0.048）、运动试验期间的心率动态（p=0.035）。添加心率变异性参数（主动直立倾斜试验期间R-R间期标准差和频谱低频成分的动态）提高了预后的准确性。通过使用构建的模型计算了风险概况。因此，心率变异性参数有助于提高模型的预后价值。
