Kunz J, Winzer K J
Institut für Pathologie, Bezirkskrankenhaus Potsdam.
Zentralbl Chir. 1991;116(7):483-6.
The S phase fraction of breast biopsies of 110 patients determined in vitro using 3H-thymidine. In fibrocystic lesions the 3H-thymidine labeling index (3H-TMI) increases parallel to the degree of dysplasia. In our opinion proliferating mastopathies are only those with a 3H-TMI of more than 1%. Invasive ductal mammary carcinomas with the histological structure demonstrate a strong variable proliferative activity histoautoradiographically as expression of their different growth dynamics.
使用³H-胸腺嘧啶核苷在体外测定了110例患者乳腺活检组织的S期分数。在纤维囊性病变中，³H-胸腺嘧啶核苷标记指数（³H-TMI）随发育异常程度平行增加。我们认为，增殖性乳腺病仅指那些³H-TMI超过1%的病变。具有该组织结构的浸润性导管乳腺癌在组织放射自显影中显示出强烈的可变增殖活性，这是其不同生长动力学的表现。
