Pérez-Pérez Lidia, Suárez Oscar, Sánchez-Aguilar Dolores, Toribio Jaime
Departamento de Dermatología, Complejo Hospitalario Universitario, Facultad de Medicina, Santiago de Compostela, Spain.
Actas Dermosifiliogr. 2005 Dec;96(10):681-4. doi: 10.1016/s0001-7310(05)73158-6.
Pemphigus vulgaris is an autoimmune disease characterized by acantholysis and intraepidermal bullae formation. The isomorphic Koebner phenomenon is a response to different stimuli, and it has been described in many skin disorders. An association between the two has rarely been described. We present a case of pemphigus vulgaris that appeared over surgical scars. Pemphigus vulgaris over scars is very rare. In our case, the reactivation of the pemphigus antigens in the surgical scar probably caused a generalized autoantibody response, with the formation of bullae on the patient's trunk.
寻常型天疱疮是一种以棘层松解和表皮内水疱形成为特征的自身免疫性疾病。同形反应（Koebner现象）是对不同刺激的一种反应，已在许多皮肤疾病中有所描述。两者之间的关联鲜有报道。我们报告一例出现在手术瘢痕上的寻常型天疱疮病例。瘢痕部位出现寻常型天疱疮非常罕见。在我们的病例中，手术瘢痕中天疱疮抗原的重新激活可能引发了全身性自身抗体反应，导致患者躯干上形成水疱。
