Ruiz de Casas Andrés, García-Bravo Begoña, Camacho Francisco
Departamento de Dermatología MQ, Hospital Virgen Macarena, Avda. Dr. Fedriani s/n, 41009 Seville, Spain.
Actas Dermosifiliogr. 2005 Mar;96(2):122-3. doi: 10.1016/s0001-7310(05)73051-9.
Adverse skin effects from interferon (IFN) plus ribavirin combined therapy are relatively frequent, but they are usually local and related to the IFN injection site. However, distant or generalized eczematous reactions secondary to this treatment are rare. The introduction of pegylated interferons may increase the frequency of these skin lesions.
干扰素（IFN）联合利巴韦林治疗产生的皮肤不良反应较为常见，但通常为局部反应，且与干扰素注射部位有关。然而，继发于该治疗的远处或全身性湿疹样反应较为罕见。聚乙二醇化干扰素的应用可能会增加这些皮肤损害的发生率。
