De Waele J, Pletinckx P, Blot S, Hoste E
Ghent University Hospital, Intensive Care Unit 1K12-C, De Pintelaan 185, 9000, Ghent, Belgium.
Intensive Care Med. 2006 Mar;32(3):455-9. doi: 10.1007/s00134-005-0062-9. Epub 2006 Feb 14.
The objective was to determine the minimum volume of instillation fluid for intra-abdominal pressure (IAP) measurement, and to evaluate the effect of instillation volume on transvesically measured IAP.
Prospective cohort study
Twenty-two-bed surgical ICU of the Ghent University Hospital.
Twenty patients at risk of intra-abdominal hypertension (IAH).
Transvesical IAP measurement using volumes from 10 to 100 ml. Minimal volume at which an IAP was measured was recorded (IAP(min)), as well as IAP at 50 and 100 ml of instillation volume (IAP(50) and IAP(100)). The percentage difference for IAP(50) and IAP(100) was calculated.
The minimal volume for IAP measurement was 10 ml in all patients. Mean IAP(min) was 12.8 mmHg (+/- 4.9), mean IAP(50 )15 mmHg (+/- 4.5) and mean IAP(100) 17.1mmHg (+/- 4.7). The mean percentage difference for IAP(50) was 21% (+/- 17%), and 40% (+/-29%) for IAP(100.) Twelve patients were categorised as suffering from IAH when 10 ml of saline was used for IAP measurement, increasing to 15 and 17 patients respectively when using 50 and 100 ml. In patients with IAH, there was a significant correlation between the duration of bladder drainage and percentage difference for IAP(100) (Pearson correlation coefficient 0.60, p = 0.03).
Using 50 or 100 ml of saline for IAP measurement in critically ill patients results in higher IAP values compared with the use of 10 ml, and possibly, in overestimation of the incidence of intra-abdominal hypertension.
确定用于测量腹腔内压力(IAP)的最小灌注液体积,并评估灌注液体积对经膀胱测量的IAP的影响。
前瞻性队列研究
根特大学医院拥有22张床位的外科重症监护病房。
20例有腹腔内高压(IAH)风险的患者。
使用10至100毫升的体积进行经膀胱IAP测量。记录测量到IAP的最小体积(IAP(min)),以及灌注体积为50和100毫升时的IAP(IAP(50)和IAP(100))。计算IAP(50)和IAP(100)的百分比差异。
所有患者测量IAP的最小体积均为10毫升。平均IAP(min)为12.8 mmHg(±4.9),平均IAP(50)为15 mmHg(±4.5),平均IAP(100)为17.1 mmHg(±4.7)。IAP(50)的平均百分比差异为21%(±17%),IAP(100)为40%(±29%)。当使用10毫升生理盐水进行IAP测量时,12例患者被归类为患有IAH,使用50和100毫升时分别增至15例和17例。在患有IAH的患者中,膀胱引流持续时间与IAP(100) 的百分比差异之间存在显著相关性(Pearson相关系数为0.6, p = 0.03)。
与使用10毫升相比,在危重症患者中使用50或100毫升生理盐水进行IAP测量会导致更高 的IAP值,并且可能高估腹腔内高压的发生率。