Chu Chih-Kai, Tseng Ham-Min, Young Yi-Ho
Department of Otolaryngology, Lo Tung Poh-Ai Hospital, Ilan, Taiwan.
Eur Arch Otorhinolaryngol. 2006 Jun;263(6):548-51. doi: 10.1007/s00405-005-0005-7. Epub 2006 Feb 14.
The aim of this study was to investigate the audiovestibular deficits in those with posterior fossa epidermoid cyst including cerebellopontine angle in two patients and cerebellum in one patient. Prior to operation, all three patients showed bilateral gaze nystagmus. Audiometry revealed mild hearing loss in two patients, and caloric test displayed canal paresis in two patients. After operation, subsidence of gaze nystagmus and recovery of caloric responses were disclosed in all patients. Two patients had both hearing and vestibular evoked myogenic potential (VEMP) results recovered to normal. In contrast, the only one who underwent craniotomy twice displayed bilateral mild hearing loss and delayed VEMPs, possibly due to operation sequela. Hence, bilateral gaze nystagmus may present as an initial sign for posterior fossa epidermoid cyst. Audiovestibular deficits in cases of epidermoid cyst are attributable to compression neuropathy, which may resolve and return to normal responses after surgery.
本研究的目的是调查后颅窝表皮样囊肿患者的视听前庭功能缺损情况,其中包括2例桥小脑角表皮样囊肿患者和1例小脑表皮样囊肿患者。术前,所有3例患者均表现为双侧凝视性眼球震颤。听力测定显示2例患者有轻度听力损失,冷热试验显示2例患者存在半规管轻瘫。术后,所有患者的凝视性眼球震颤均减轻,冷热反应恢复。2例患者的听力和前庭诱发肌源性电位(VEMP)结果均恢复正常。相比之下,唯一接受过两次开颅手术的患者出现双侧轻度听力损失和VEMP延迟,这可能是手术后遗症所致。因此,双侧凝视性眼球震颤可能是后颅窝表皮样囊肿的首发症状。表皮样囊肿病例的视听前庭功能缺损归因于压迫性神经病变,术后可能会缓解并恢复正常反应。