Schröter Matthias, Speicher Angelika, Hofmann Jörg, Roggentin Peter
Landesinstitut für den Offentlichen Gesundheitsdienst NRW, Von-Stauffenberg-Strasse 36, 48151 Münster, Germany.
Environ Microbiol. 2006 Mar;8(3):556-9. doi: 10.1111/j.1462-2920.2005.00934.x.
Besides the 'classical' animals known as reservoirs for Salmonella spp., like poultry and cattle, reptiles have emerged as a significant source of human salmonellae infections during the last years. Reptile-associated salmonellae frequently cause severe clinical courses including fatalities due to septicaemia and meningitis. Therefore, it is of major priority to develop measures which may help preventing cases of reptile-associated salmonellae. However, as a first step the epidemiology of salmonellae in reptiles must be understood. Therefore, in this study a population analysis of the salmonellae of two female snakes was performed and the pattern of inheritance of salmonellae to their offspring was investigated. It is demonstrated that adult snakes usually harbour a population of concurrent salmonellae serovars. Colonization of their offspring during pregnancy and birth is a significant way of transmission causing 65% of the newborn to be positive for salmonellae. The effectiveness of the transmission does not seem to be due only to the frequency of a certain serovar, because the most prevailing strain of one female snake was not detectable in any of her offspring.
除了作为沙门氏菌属宿主的“经典”动物，如家禽和牛之外，在过去几年中，爬行动物已成为人类沙门氏菌感染的一个重要来源。与爬行动物相关的沙门氏菌经常导致严重的临床病程，包括因败血症和脑膜炎导致的死亡。因此，制定有助于预防与爬行动物相关的沙门氏菌病例的措施是首要任务。然而，作为第一步，必须了解爬行动物中沙门氏菌的流行病学情况。因此，在本研究中，对两条雌蛇的沙门氏菌进行了种群分析，并研究了沙门氏菌向其后代的遗传模式。结果表明，成年蛇通常携带一群并发的沙门氏菌血清型。在怀孕和出生期间其后代的定植是一种重要的传播方式，导致65%的新生儿沙门氏菌检测呈阳性。传播的有效性似乎不仅仅取决于某种血清型的频率，因为一条雌蛇最普遍的菌株在其任何后代中都未检测到。
