标准博弈法得出的外科手术患者麻醉后状态的效用
Utilities of the post-anesthesia state derived by the standard gamble method in surgical patients.
作者信息
Rashiq Saifudin, Edlund Diane, Dick Bruce D
机构信息
Department of Anesthesiology & Pain Medicine, University of Alberta, Edmonton, AB T6G 2G3, Canada.
出版信息
BMC Med Inform Decis Mak. 2006 Feb 15;6:8. doi: 10.1186/1472-6947-6-8.
BACKGROUND
There are no published utilities for the post-anesthesia state obtained by the standard gamble method (SG).
METHODS
We obtained utilities for postoperative pain, nausea, vomiting, urinary retention and myalgia from 100 adults prior to elective surgery using SG.
RESULTS
20% of volunteer participants could not demonstrate a satisfactory understanding of the SG process. Median utilities for each adverse effect were all very close to 1.0, and no statistically significant differences were found between them.
CONCLUSION
Our results suggest that the avoidance of anesthesia related side effects and pain is not viewed by patients prior to surgery as being worthy of the taking of even a miniscule risk of death. This may affect the decision to utilize anesthesia techniques that trade a lower incidence of common side effects for a very low but finite risk of a catastrophic complication.
背景
目前尚无通过标准博弈法（SG）得出的麻醉后状态效用值的相关报道。
方法
我们在择期手术前，使用SG法从100名成年人中获取了术后疼痛、恶心、呕吐、尿潴留和肌痛的效用值。
结果
20%的志愿者参与者对SG过程未能表现出令人满意的理解。每种不良反应的中位效用值均非常接近1.0，且它们之间未发现统计学上的显著差异。
结论
我们的结果表明，手术前患者并不认为避免麻醉相关副作用和疼痛值得冒哪怕极小的死亡风险。这可能会影响麻醉技术的选择决策，即采用较低常见副作用发生率但有极低但确切灾难性并发症风险的麻醉技术。
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