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良性前列腺增生症手术治疗的技术与长期疗效

Techniques and long-term results of surgical procedures for BPH.

作者信息

Reich Oliver, Gratzke Christian, Stief Christian G

机构信息

Department of Urology, University-Hospital Munich Grosshadern, Ludwig-Maximilians-University, Germany.

出版信息

Eur Urol. 2006 Jun;49(6):970-8; discussion 978. doi: 10.1016/j.eururo.2005.12.072. Epub 2006 Feb 6.

Abstract

OBJECTIVE

To provide an overview on the current status of the long-term outcomes of instrumental treatment options for patients with lower urinary tract symptoms that are suggestive of bladder outlet obstruction.

METHODS

Based on MEDLINE database searches, we performed a systematic review of the literature with a focus on peer-reviewed articles about surgical benign prostatic hyperplasia (BPH) therapy published between 2000 and 2005. Special emphasis was given to randomized controlled trials on long-term outcome with a minimum follow-up of five years.

RESULTS

Data on clinical outcome with a follow-up of more than 10 years are available for open prostatectomy (OP), transurethral resection of the prostate (TURP), and transurethral microwave therapy. Studies with a follow-up of at least five years are obtainable for transurethral incision of the prostate, transurethral vaporisation of the prostate, transurethral needle ablation of the prostate, Holmium:YAG laser enucleation of the prostate, potassium-titanyl-phosphate laser vaporization of the prostate, and interstitial laser coagulation of the prostate. Among these long-term reports, OP and TURP provide the most durable results.

CONCLUSIONS

The most substantial long-term data on surgical procedures for BPH are available for conventional therapy, namely TURP. Concerning the techniques that have emerged within the last decade, there is clear evidence that the outcomes are more sustainable for truly ablative and thus deobstructing procedures.

摘要

目的

概述对提示膀胱出口梗阻的下尿路症状患者进行器械治疗的长期疗效现状。

方法

基于医学文献数据库检索,我们对文献进行了系统回顾,重点关注2000年至2005年间发表的关于手术治疗良性前列腺增生(BPH)的同行评议文章。特别强调了随访至少五年的长期疗效随机对照试验。

结果

对于开放性前列腺切除术(OP)、经尿道前列腺电切术(TURP)和经尿道微波治疗,有随访超过10年的临床疗效数据。对于经尿道前列腺切开术、经尿道前列腺汽化术、经尿道前列腺针刺消融术、钬激光前列腺剜除术、磷酸钛钾激光前列腺汽化术和前列腺间质激光凝固术,有随访至少五年的研究。在这些长期报告中,OP和TURP提供了最持久的疗效。

结论

关于BPH手术治疗的最丰富长期数据来自传统疗法,即TURP。对于过去十年出现的技术,有明确证据表明,真正的消融性手术(从而解除梗阻)的疗效更持久。

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