缺血性起源的单纯孤立性单侧核间性眼肌麻痹：一例报告及文献复习
Pure isolated unilateral internuclear ophthalmoplegia from ischemic origin: report of a case and literature review.
作者信息
Deleu D, Sokrab T, Salim K, El Siddig A, Hamad A A
机构信息
Department of Neurology (Medicine), Hamad Medical Corporation, P.O. Box 3050, Doha, State of Qatar.
出版信息
Acta Neurol Belg. 2005 Dec;105(4):214-7.
PURPOSE
To report a case of pure isolated unilateral internuclear ophthalmoplegia from ischemic stroke, and to review its literature.
METHODS
A 55-year old man, with a history of long-standing diabetes mellitus, developed acute-onset left internuclear ophthalmoplegia. MRI revealed a small paramedian dorsal pontine infarct ventral and lateral to the aquaductus cerebri. Intracranial MR angiography was normal. A systematic search was performed of the literature from January 1980 to December 2004 by using MEDLINE and EMBASE. Case reports with or series including patients with negative MRI findings were excluded.
RESULTS
Nine cases of pure isolated MRI-proven unilateral INO resulting from ischemic stroke including this one, have been reported. In over 75% recovery was reported.
CONCLUSION
Isolated unilateral internuclear ophthalmoplegia can be the sole manifestation of ischemic stroke and generally carries a good prognosis.
目的
报告一例因缺血性卒中导致的单纯性孤立性单侧核间性眼肌麻痹病例，并对其相关文献进行综述。
方法
一名55岁男性，有长期糖尿病病史，突发急性左侧核间性眼肌麻痹。MRI显示脑桥背侧中线上一个小梗死灶，位于大脑导水管腹侧和外侧。颅内MR血管造影正常。通过使用MEDLINE和EMBASE对1980年1月至2004年12月的文献进行了系统检索。排除了MRI结果为阴性的患者的病例报告或系列研究。
结果
包括本病例在内，已报告9例经MRI证实的因缺血性卒中导致的单纯性孤立性单侧核间性眼肌麻痹病例。报告显示超过75%的患者恢复。
结论
孤立性单侧核间性眼肌麻痹可以是缺血性卒中的唯一表现，并且通常预后良好。
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