Xie Xiao-jun, Jiang Xue-Wu
Department of Pediatric Surgery, the Second Hospital of Shantou University Medical College, Shantou, Guangdong 515041, China.
Zhonghua Nan Ke Xue. 2006 Jan;12(1):68-70.
Testicular descent is an essential step in the course of reproductive system development. The mechanisms involved in the regulation of testis descent is not distinct. Gubernaculum has a very close relationship with testis descent. Maldescent of testis can cause abnormalities of genital system such as testicular underwent (cryptorchidism), dysplasia, tumor, infertility and low sexuality. Recently insulin like hormone 3 is a hotspot of concerning affecting gubernacular development and testicular descent. This article briefly reviews the advances in these aspects.
睾丸下降是生殖系统发育过程中的一个重要步骤。睾丸下降调节所涉及的机制尚不清楚。引带与睾丸下降关系密切。睾丸下降异常可导致生殖系统异常,如睾丸未降(隐睾)、发育异常、肿瘤、不育和性功能低下。近年来,胰岛素样激素3是影响引带发育和睾丸下降的一个研究热点。本文简要综述这些方面的研究进展。