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支架置入术后的辅助球囊后扩张:对于药物洗脱支架而言是否仍有必要?

Adjunctive balloon postdilatation after stent deployment: is it still necessary with drug-eluting stents?

作者信息

Brodie Bruce R

机构信息

Moses Cone Heart and Vascular Center, LeBauer Cardiovascular Research Foundation, Greensboro, North Carolina 27401, USA.

出版信息

J Interv Cardiol. 2006 Feb;19(1):43-50. doi: 10.1111/j.1540-8183.2006.00103.x.

Abstract

Deployment of bare metal stents (BMS) with current stent delivery systems is often associated with suboptimal stent expansion. Adjunctive postdilatation with noncompliant balloons has improved stent expansion with BMS and has been associated with less need for target vessel revascularization (TVR). Drug-eluting stents (DES) have proven highly effective in reducing restenosis and TVR and are now being used in the great majority of percutaneous coronary interventions. Because of the very low rates of TVR with DES, many operators have felt that postdilatation may no longer be necessary. In this review, we present data showing that stent expansion of DES (like BMS) using current stent delivery systems is frequently suboptimal. Furthermore, smaller mimimal stent area (MSA) and stent underexpansion following deployment of DES are strong predictors of stent thrombosis and TVR. Adjunctive postdilatation with noncompliant balloons can increase MSA and decrease the frequency of suboptimal stent deployment and potentially can reduce the frequency of stent thrombosis and TVR. Despite the lack of evidence from randomized clinical trials, we believe the observational data support the use of adjunctive balloon postdilatation following deployment of DES in the great majority of patients.

摘要

使用当前的支架输送系统植入裸金属支架(BMS)常常与支架扩张不理想相关。使用非顺应性球囊进行辅助性后扩张改善了BMS的支架扩张情况,并与降低靶血管血运重建(TVR)需求相关。药物洗脱支架(DES)已被证明在减少再狭窄和TVR方面非常有效,目前在绝大多数经皮冠状动脉介入治疗中都在使用。由于DES的TVR发生率非常低,许多术者认为可能不再需要进行后扩张。在本综述中,我们展示的数据表明,使用当前的支架输送系统时,DES(与BMS一样)的支架扩张常常不理想。此外,DES植入后较小的最小支架面积(MSA)和支架扩张不足是支架血栓形成和TVR的强烈预测因素。使用非顺应性球囊进行辅助性后扩张可增加MSA,降低支架植入不理想的频率,并有可能降低支架血栓形成和TVR的频率。尽管缺乏随机临床试验的证据,但我们认为观察性数据支持在绝大多数患者中DES植入后使用辅助性球囊后扩张。

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