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当代左主干经皮冠状动脉介入治疗:最新综述

Contemporary Left Main Percutaneous Coronary Intervention: A State-of-the-art Review.

作者信息

Showkathali Refai, Yalamanchi Radha Priya

机构信息

Department of Cardiology, Apollo Main Hospital Chennai, India.

出版信息

Interv Cardiol. 2023 May 26;18:e20. doi: 10.15420/icr.2023.02. eCollection 2023.

DOI:10.15420/icr.2023.02
PMID:37435600
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10331562/
Abstract

The majority of the left ventricular myocardium is supplied by the left main coronary artery. Atherosclerotic obstruction of the left main coronary artery therefore leads to significant myocardial jeopardy. Coronary artery bypass surgery (CABG) has been the gold standard for left main coronary artery disease in the past. However, advancements in technology have established percutaneous coronary intervention (PCI) as a standard, safe and reasonable alternative to CABG, with comparable outcomes. Contemporary PCI of left main coronary artery disease comprises careful patient selection, accurate technique guided by either intravascular ultrasound or optical coherence tomography and - if necessary - physiological assessment using fractional flow reserve. This review focuses on current evidence from registries and randomised trials comparing PCI with CABG, procedural tips and tricks, adjuvant technologies and the triumph of PCI.

摘要

大部分左心室心肌由左冠状动脉主干供血。因此,左冠状动脉主干的动脉粥样硬化性阻塞会导致严重的心肌危险。在过去,冠状动脉旁路移植术(CABG)一直是治疗左冠状动脉主干疾病的金标准。然而,技术的进步已使经皮冠状动脉介入治疗(PCI)成为CABG的一种标准、安全且合理的替代方法,二者疗效相当。当代对左冠状动脉主干疾病的PCI包括仔细的患者选择、由血管内超声或光学相干断层扫描引导的精确技术,以及必要时使用血流储备分数进行的生理评估。本综述重点关注来自登记研究和随机试验的当前证据,这些研究比较了PCI与CABG、手术技巧、辅助技术以及PCI的优势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8e2/10331562/78aca16f8984/icr-18-e20-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8e2/10331562/c2ff4f1d3d9d/icr-18-e20-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8e2/10331562/7f0e52c39326/icr-18-e20-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8e2/10331562/1d544d337759/icr-18-e20-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8e2/10331562/78aca16f8984/icr-18-e20-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8e2/10331562/c2ff4f1d3d9d/icr-18-e20-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8e2/10331562/7f0e52c39326/icr-18-e20-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8e2/10331562/1d544d337759/icr-18-e20-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8e2/10331562/78aca16f8984/icr-18-e20-g004.jpg

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2
The Use of Bumper Wire Technique and Intravascular Ultrasound for Precise Aorto-Ostial Stenting.使用球囊导管技术和血管内超声进行精确的主动脉开口支架置入术。
Front Cardiovasc Med. 2022 Jul 14;9:929472. doi: 10.3389/fcvm.2022.929472. eCollection 2022.
3
2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.
[Clinical outcomes of percutaneous intervention on the unprotected left main coronary artery].[非保护左主干冠状动脉经皮介入治疗的临床结果]
Rev Med Inst Mex Seguro Soc. 2024 Jan 8;62(1):1-8. doi: 10.5281/zenodo.10278143.
4
Prognostic Impact of a Routine Six-Month Exercise Stress Test after Complex Left Main Bifurcation Percutaneous Intervention.复杂左主干分叉经皮介入术后常规六个月运动负荷试验的预后影响
Diagnostics (Basel). 2023 Dec 26;14(1):59. doi: 10.3390/diagnostics14010059.
2021年美国心脏病学会/美国心脏协会/心血管造影和介入学会冠状动脉血运重建指南:美国心脏病学会/美国心脏协会临床实践指南联合委员会报告
Circulation. 2022 Jan 18;145(3):e18-e114. doi: 10.1161/CIR.0000000000001038. Epub 2021 Dec 9.
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