Westling Katarina, Farra Anna, Cars Björn, Ekblom Anna Gerber, Sandstedt Karin, Settergren Bo, Wretlind Bengt, Jorup Christina
Division of Infectious Diseases, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Huddinge, I 73, SE 141 86 Stockholm, Sweden.
J Infect. 2006 Dec;53(6):403-7. doi: 10.1016/j.jinf.2006.01.001. Epub 2006 Feb 14.
The rate of infection following cat bites appears to be greater than that from dog bites. To study the clinical picture, complications and microbiology (in humans and cats), this prospective study was performed.
A prospective study with patients with clinical symptoms of infection due to cat bites from three emergency wards during two years in Stockholm, Sweden. Aerobic and anaerobic cultures from the wounds were performed as well as cultures from the biting cat's mouth. Clinical data and complications were registered.
Seventy-nine episodes in 78 patients with infective cat bites were included. Pasteurella multocida was isolated in 70% of the patients; in addition anaerobic pathogens were isolated in 16% concurrently with P. multocida, while Staphylococcus aureus was isolated in only two patients. Pasteurella spp. was also isolated from 80% of the pharynx of the biting cats. The dominating symptoms of infection were erythema, pain and oedema, often emerging as early as 3h after the bite. Complications such as tendosynovitis, arthritis, abscesses and septicaemia occurred in 18% of the patients. No patient died due to the infection. The majority of the patients received penicillin or amoxicillin as antibiotic treatment.
P. multocida was the dominating pathogen among patients with infected cat bites and antibiotic treatment should cover P. multocida.
猫咬伤后的感染率似乎高于狗咬伤。为研究临床症状、并发症及微生物学情况（包括人类和猫的），开展了这项前瞻性研究。
对瑞典斯德哥尔摩三个急诊病房在两年内因猫咬伤出现感染临床症状的患者进行前瞻性研究。对伤口进行需氧和厌氧培养，同时对咬人的猫的口腔进行培养。记录临床数据和并发症情况。
纳入了78例感染性猫咬伤患者的79次发病情况。70%的患者分离出多杀巴斯德菌；此外，16%的患者同时分离出厌氧病原体和多杀巴斯德菌，而仅在两名患者中分离出金黄色葡萄球菌。80%的咬人的猫的咽部也分离出巴斯德菌属。感染的主要症状为红斑、疼痛和水肿，通常在咬伤后3小时内就会出现。18%的患者出现肌腱炎、关节炎、脓肿和败血症等并发症。没有患者因感染死亡。大多数患者接受青霉素或阿莫西林作为抗生素治疗。
多杀巴斯德菌是感染性猫咬伤患者中的主要病原体，抗生素治疗应覆盖多杀巴斯德菌。
