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[家禽传染性贫血疫苗接种(CAA)——现场研究结果]

[Vaccination against infectious anemia of poultry (CAA)--results of field studies].

作者信息

Vielitz E, Conrad C, Voss M, von Bülow V, Dorn P, Bachmeier J, Löhren U

机构信息

Veterinärlabor der Fa. Lohmann Tierzucht, Cuxhaven.

出版信息

Dtsch Tierarztl Wochenschr. 1991 Apr;98(4):144-7.

PMID:1648475
Abstract

Infectious anemia of poultry is a disease of high economical significance. Connatal infection of chicks with the chicken anemia agent (CAA) via the embryonated egg causes anemia along with severe immunosuppression, thus rendering the chicken susceptible for secondary infections. In order to prevent infection of young chicks, it is necessary to induce immunity against CAA in parent flocks, with the aim to prevent connatal spread of the infection and provide maternal protection for baby chicks. In this publication, the efficacy and use of a live CAA vaccine is reported. From autumn 1986 until summer 1990, 3 experimental vaccine charges were applied in 85 broiler parent flocks with totally 3.1 million chickens. In addition, totally 293,000 broiler breeder and 171,000 layer breeder chicken were vaccinated in 1989/90. The vaccine was administered between the 13th and 19th week of life by drinking water without adverse effect to the birds. Chicken anemia symptoms were observed only at the begin of laying period in two parent flocks. These flocks had been vaccinated in the 17th and 19th week, respectively. The offsprings of all other vaccinated parent flocks remained free of chicken anemia. Day-old chicks derived from vaccinated parent flocks were protected against CAA challenge infection. It is emphasized, that vaccination should be performed within the 13th to 15th week of life, because according to our observations, this will lead to an immediate seroconversion.

摘要

家禽传染性贫血是一种具有高度经济意义的疾病。雏鸡通过感染有胚胎的鸡蛋先天性感染鸡贫血因子(CAA)会导致贫血以及严重的免疫抑制,从而使鸡易受继发感染。为了预防雏鸡感染,有必要在种鸡群中诱导针对CAA的免疫力,以防止感染的先天性传播并为雏鸡提供母源保护。在本出版物中,报告了一种活CAA疫苗的功效和使用情况。从1986年秋季到1990年夏季,在85个肉鸡种鸡群中应用了3批实验性疫苗,共计310万只鸡。此外,在1989/90年,总共29.3万只肉种鸡和17.1万只蛋种鸡接种了疫苗。该疫苗在鸡13至19周龄时通过饮水给药,对鸡没有不良影响。仅在两个种鸡群产蛋期开始时观察到鸡贫血症状。这两个鸡群分别在第17周和第19周接种了疫苗。所有其他接种疫苗的种鸡群的后代均未出现鸡贫血。来自接种疫苗的种鸡群的一日龄雏鸡受到保护,免受CAA攻击感染。需要强调的是,疫苗接种应在鸡13至15周龄时进行,因为根据我们的观察,这将导致立即发生血清转化。

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