Noninvasive assessment of coronary artery disease in diabetic patients: the role of stress echocardiography.

Diabetes mellitus is a frequently occurring disease, and its prognosis is essentially related to cardiac complications. Some have suggested that these patients should be considered as coronary artery disease (CAD)-equivalent and treated aggressively, accordingly. In addition, CAD in diabetes patients at the time of diagnosis is often more advanced, and is frequently associated with more extensive disease, a greater incidence of left ventricular dysfunction and higher rates of cardiac events. Unfortunately, the standard exercise treadmill stress test has important limitations, with a poor sensitivity for CAD detection if the patient has limited exercise capacity, which is the case for more than one-half of the diabetic patients in some series. The detection of regional wall motion abnormality with echocardiography permits the identification of the coronary territory involved. It can be used for CAD diagnosis, evaluation of myocardial viability, risk stratification following a myocardial infarction and assessment of preoperative risk before noncardiac surgery. The risk of CAD in patients with diabetes mellitus is reviewed, and the role of noninvasive testing with stress echocardiography in the diagnosis and risk stratification of these patients is discussed.