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[葡萄糖-6-磷酸脱氢酶缺乏症患者的麻醉:病例报告及围手术期麻醉管理]

[Anesthesia in patients with glucose-6-phosphate dehydrogenase deficiency: case report and perioperative anesthesiologic management].

作者信息

Depta A L, Erdös G, Werner C

机构信息

Klinik für Anästhesiologie, Johannes Gutenberg-Universität, Mainz, Germany.

出版信息

Anaesthesist. 2006 May;55(5):550-4. doi: 10.1007/s00101-005-0971-6.

Abstract

Glucose-6-phosphate dehydrogenase (G6PD) deficiency, a frequent congenital human enzyme defect, is the most frequent cause of hemolytic anemia triggered by drugs or infectious diseases. Drugs which induce acute hemolysis in patients with G6PD deficiency are often used in anesthesia and perioperative pain therapy. Considering the fact that patients from geographic regions with a high prevalence of the disease are often treated in European hospitals, special attention should be paid to this problem. We report a case of a 30-year-old female patient with favism and review the disease and anesthesia-related implications.

摘要

葡萄糖-6-磷酸脱氢酶(G6PD)缺乏症是一种常见的先天性人类酶缺陷,是由药物或传染病引发的溶血性贫血的最常见原因。可在G6PD缺乏症患者中诱发急性溶血的药物常用于麻醉和围手术期疼痛治疗。鉴于来自该疾病高流行地区的患者常在欧洲医院接受治疗,应特别关注这一问题。我们报告一例30岁患有蚕豆病的女性患者病例,并综述该疾病及与麻醉相关的影响。

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