Nihashi Takashi, Ito Kengo, Kato Takashi, Kato Rikio, Okuda Makiko, Arima Toru, Bundo Masahiko, Kawatsu Shoji, Hayasaka Kazumasa, Ishigaki Takeo
Department of Radiology, National Center for Geriatrics and Gerontology, Ohbu, Japan.
Ann Nucl Med. 2006 Jan;20(1):75-8. doi: 10.1007/BF02985595.
The source of a fever of unknown origin (FUO) and watery diarrhea in a 63-yr-old female with a history of disturbance of consciousness due to moyamoya disease was examined. Fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET), colonoscopy, blood analysis, and determination of cytomegalovirus (CMV) antigenemia were performed. FDG was found to be accumulated in the wall of a dilated colon, and extended from the transverse to sigmoid colon. Colonoscopy revealed edematous, inflammatory, and punched out lesions in accordance with the areas of abnormal FDG uptake. A biopsy specimen showed the antibody of CMV in the colonic mucosa, and CMV antigenemia was detected by an immunohistochemical assay using a monoclonal antibody for CMV pp65 antigen. From these findings, we strongly suspected CMV enteritis.
