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尽管心房颤动是射频导管消融治疗心房扑动术后的高发并发症,但该治疗仍能带来长期的症状改善。

Long-term symptomatic benefit after radiofrequency catheter ablation for atrial flutter despite a high incidence of post-procedural atrial fibrillation.

作者信息

Anné Wim, Willems Rik, Adriaenssens Bert, Adams Jozef, Ector Hugo, Heidbüchel Hein

机构信息

Department of Cardiology, Gasthuisberg University Hospital, University of Leuven, Leuven, Belgium.

出版信息

Acta Cardiol. 2006 Feb;61(1):75-82. doi: 10.2143/AC.61.1.2005143.

Abstract

OBJECTIVE

A high proportion of patients develops atrial fibrillation (AF) after ablation for atrial flutter (AFL). Radiofrequency ablation for AFL therefore would only be useful if it leads to a better quality of life despite this high incidence of AF post-ablation.

METHODS

All patients who underwent AFL ablation in our centre before March 2002 (n=203) were contacted by letter a median of 2.3 years after their ablation. Sixty-eight percent answered the questionnaire polling the perceived benefits of the procedure. The results were stratified according to the presenting arrhythmia before the ablation: only AFL, predominantly AFL, predominantly AF or class Ic-III AFL.

RESULTS

Despite a 60% incidence of AF, 84% considered the procedure to be beneficial during the 1st year and 77% during the 2nd year post-ablation. Patients with predominantly AF before the procedure showed significantly less overall improvement than the 3 other groups (50% and 33% after I year and 2 years, p< 0.01) and a smaller reduction in palpitations (50% and 29% after I year and 2 years, p < 0.01). The benefit of an ablation was also significantly less in patients who developed AF post-ablation than in patients who were completely arrhythmia free (75% versus 98% 1st year, 58% versus 91% 2nd year; p 0.01); nevertheless 75% of these patients reported fewer palpitations and 56% tolerated symptoms better than before.

CONCLUSIONS

Despite a high incidence of AF after AFL ablation, the majority of patients considered the intervention beneficial. Only in patients with predominantly AF before ablation the procedure does not seem beneficial.

摘要

目的

很大一部分患者在心房扑动(AFL)消融术后会发生心房颤动(AF)。因此,对于AFL的射频消融术,只有在尽管消融术后AF发生率较高但仍能带来更好生活质量的情况下才有用。

方法

2002年3月前在本中心接受AFL消融术的所有患者(n = 203)在消融术后中位2.3年通过信件进行联系。68%的患者回复了关于该手术感知益处的问卷。结果根据消融术前出现的心律失常进行分层:仅AFL、以AFL为主、以AF为主或Ic - III类AFL。

结果

尽管AF发生率为60%,但84%的患者认为该手术在术后第1年有益,77%的患者认为在术后第2年有益。术前以AF为主的患者总体改善明显少于其他3组(术后1年和2年分别为50%和33%,p < 0.01),心悸减少也较少(术后1年和2年分别为50%和29%,p < 0.01)。消融术后发生AF的患者的手术益处也明显少于完全无心律失常的患者(第1年为75%对98%,第2年为58%对91%;p < 0.01);然而,这些患者中有75%报告心悸减少,56%的患者症状耐受性比以前更好。

结论

尽管AFL消融术后AF发生率较高,但大多数患者认为该干预有益。仅在术前以AF为主的患者中,该手术似乎没有益处。

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