Anné Wim, Willems Rik, Adriaenssens Bert, Adams Jozef, Ector Hugo, Heidbüchel Hein
Department of Cardiology, Gasthuisberg University Hospital, University of Leuven, Leuven, Belgium.
Acta Cardiol. 2006 Feb;61(1):75-82. doi: 10.2143/AC.61.1.2005143.
A high proportion of patients develops atrial fibrillation (AF) after ablation for atrial flutter (AFL). Radiofrequency ablation for AFL therefore would only be useful if it leads to a better quality of life despite this high incidence of AF post-ablation.
All patients who underwent AFL ablation in our centre before March 2002 (n=203) were contacted by letter a median of 2.3 years after their ablation. Sixty-eight percent answered the questionnaire polling the perceived benefits of the procedure. The results were stratified according to the presenting arrhythmia before the ablation: only AFL, predominantly AFL, predominantly AF or class Ic-III AFL.
Despite a 60% incidence of AF, 84% considered the procedure to be beneficial during the 1st year and 77% during the 2nd year post-ablation. Patients with predominantly AF before the procedure showed significantly less overall improvement than the 3 other groups (50% and 33% after I year and 2 years, p< 0.01) and a smaller reduction in palpitations (50% and 29% after I year and 2 years, p < 0.01). The benefit of an ablation was also significantly less in patients who developed AF post-ablation than in patients who were completely arrhythmia free (75% versus 98% 1st year, 58% versus 91% 2nd year; p 0.01); nevertheless 75% of these patients reported fewer palpitations and 56% tolerated symptoms better than before.
Despite a high incidence of AF after AFL ablation, the majority of patients considered the intervention beneficial. Only in patients with predominantly AF before ablation the procedure does not seem beneficial.
很大一部分患者在心房扑动(AFL)消融术后会发生心房颤动(AF)。因此,对于AFL的射频消融术,只有在尽管消融术后AF发生率较高但仍能带来更好生活质量的情况下才有用。
2002年3月前在本中心接受AFL消融术的所有患者(n = 203)在消融术后中位2.3年通过信件进行联系。68%的患者回复了关于该手术感知益处的问卷。结果根据消融术前出现的心律失常进行分层:仅AFL、以AFL为主、以AF为主或Ic - III类AFL。
尽管AF发生率为60%,但84%的患者认为该手术在术后第1年有益,77%的患者认为在术后第2年有益。术前以AF为主的患者总体改善明显少于其他3组(术后1年和2年分别为50%和33%,p < 0.01),心悸减少也较少(术后1年和2年分别为50%和29%,p < 0.01)。消融术后发生AF的患者的手术益处也明显少于完全无心律失常的患者(第1年为75%对98%,第2年为58%对91%;p < 0.01);然而,这些患者中有75%报告心悸减少,56%的患者症状耐受性比以前更好。
尽管AFL消融术后AF发生率较高,但大多数患者认为该干预有益。仅在术前以AF为主的患者中,该手术似乎没有益处。