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人血清对SA - 11轮状病毒血凝反应的非抗体抑制剂

Human serum non-antibody inhibitors towards SA-11 rotavirus hemagglutination.

作者信息

Superti F, Marchetti M, Seganti L, Conte M P, Orsi N

机构信息

Laboratorio di Ultrastrutture, Istituto Superiore di Sanità, Roma.

出版信息

Microbiologica. 1991 Jan;14(1):25-30.

PMID:1648658
Abstract

In the present work the non-antibody inhibitory activity of human serum towards SA-11 rotavirus hemagglutination (HA) has been studied. Among human serum protein components, inhibitory activity was recovered in fractions III (beta-globulin), IV (alpha-globulin) and IV (glycoprotein). Additional experiments performed with purified lipoprotein sub-classes and their lipid and apolipoprotein moieties demonstrated the ability of HDL and, HDL1 to prevent SA-11 HA.

摘要

在本研究中,已对人血清对SA - 11轮状病毒血凝(HA)的非抗体抑制活性进行了研究。在人血清蛋白成分中,在组分III(β-球蛋白)、IV(α-球蛋白)和IV(糖蛋白)中检测到抑制活性。对纯化的脂蛋白亚类及其脂质和载脂蛋白部分进行的额外实验表明,高密度脂蛋白(HDL)和HDL1能够抑制SA - 11 HA。

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