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硫酸沙丁胺醇和阿尔德辛导致气管造口周围接触性皮炎

Contact dermatitis around a tracheostoma due to salbutamol sulfate and Aldecin.

作者信息

Tsuruta Daisuke, Sowa Junko, Kobayashi Hiromi, Ishii Masamitsu

机构信息

Department of Dermatology, Osaka City University Graduate School of Medicine, Osaka, Japan.

出版信息

Contact Dermatitis. 2006 Feb;54(2):121-2. doi: 10.1111/j.0105-1873.2006.0560c.x.

DOI:10.1111/j.0105-1873.2006.0560c.x
PMID:16487287
Abstract

Contact dermatitis around a tracheostoma is quite rare. So far, there have been only 2 reports about this in medical literature. We, in this study, report herewith contact dermatitis in a 61-year-old Japanese man around a tracheostoma due to salbutamol sulfate and Aldecin. The patient used inhaled Sultanol and Aldecin for the treatment for allergic asthma. On examination, it was found that there was lichenified, exudative erythema with pigmentation around the tracheostoma. Patch testing with 1% aq. Sultanol and Aldecin revealed a positive reaction. Furthermore, patch testing for salbutamol sulfate 1% pet. also showed positive reaction. Although the contact allergen of our patient has not been fully determined (beclomethasone or other ingredients), this must be the first reported case of double contact dermatitis around a tracheostoma from salbutamol and Aldecin.

摘要

气管造口周围的接触性皮炎相当罕见。到目前为止,医学文献中仅有2例相关报道。在本研究中,我们在此报告一名61岁日本男性因硫酸沙丁胺醇和安特酰胺导致气管造口周围发生接触性皮炎。该患者使用吸入性速坦诺和安特酰胺治疗过敏性哮喘。检查发现,气管造口周围有苔藓化、渗出性红斑伴色素沉着。用1%水合速坦诺和安特酰胺进行斑贴试验显示阳性反应。此外,对1%石油醚沙丁胺醇进行斑贴试验也显示阳性反应。虽然该患者的接触变应原尚未完全确定(倍氯米松或其他成分),但这肯定是首例报道的因沙丁胺醇和安特酰胺导致气管造口周围双重接触性皮炎的病例。

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