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非结核分枝杆菌和鸟分枝杆菌复合群菌种鉴定报告延迟的原因及临床后果。

Causes of and clinical sequelae of delays in reporting species identification of mycobacteria other than Mycobacterium tuberculosis and Mycobacterium avium complex.

作者信息

Ooi Say Tat, Fekete Thomas

机构信息

Section of Infectious Diseases, Temple University School of Medicine, Philadelphia, PA 19140, USA.

出版信息

Diagn Microbiol Infect Dis. 2006 May;55(1):69-73. doi: 10.1016/j.diagmicrobio.2005.12.005. Epub 2006 Feb 20.

Abstract

We tracked cultures submitted to a laboratory in 2004 in which mycobacteria other than Mycobacterium tuberculosis or Mycobacterium avium complex were grown (n = 11). We reviewed clinical information, other mycobacterial cultures, and radiologic findings. We measured the time from specimen submission to first growth and to final species identification. We assessed the response to this information based on notes, laboratory tests, consultations, and radiology studies. The median time to identification was 68 days (47-292 days). In 5 cases, the clinician failed to retrieve the data, and in 3 of these cases, there was a resultant loss of opportunity to treat. In 3 cases, the laboratory never reported a definitive species, and in 3 cases, the culture results were clinically unimportant. We show that the results of positive cultures of these mycobacteria are effectively lost because they are not available in a timely fashion, and even when available, the results are overlooked.

摘要

我们追踪了2004年提交至某实验室的培养物,这些培养物中培养出了除结核分枝杆菌或鸟分枝杆菌复合群之外的分枝杆菌(n = 11)。我们查阅了临床信息、其他分枝杆菌培养物以及放射学检查结果。我们测定了从标本提交到首次生长以及到最终菌种鉴定的时间。我们根据记录、实验室检查、会诊以及放射学研究评估了对这些信息的反应。鉴定的中位时间为68天(47 - 292天)。在5例病例中,临床医生未能获取数据,其中3例因此失去了治疗机会。在3例病例中,实验室从未报告明确的菌种,在3例病例中,培养结果在临床上并不重要。我们发现,这些分枝杆菌阳性培养结果实际上被浪费了,因为它们未能及时提供,即便提供了,结果也被忽视了。

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