Graziani E, Zelent M E, Pelliccioni G A
Università degli Studi di Bologna.
Mondo Ortod. 1991 Jan-Feb;16(1):77-84.
The orthodontic tooth movement produces physical and biochemical reactions in the periodontium. Tooth movements can be expressed by cell activation inducing bone resorption and remodelling. Substances as cAMP, cGMP, neuropeptides, prostaglandins and ormons play a basic role in this mechanism as mediators and modulators of the cellular responses. The Authors review the possibility to control the degree of the tooth movement acting on this biochemical process.
正畸牙齿移动会在牙周组织中产生物理和生化反应。牙齿移动可通过诱导骨吸收和重塑的细胞激活来体现。环磷酸腺苷(cAMP)、环磷酸鸟苷(cGMP)、神经肽、前列腺素和激素等物质在这一机制中作为细胞反应的介质和调节剂发挥着基础作用。作者们综述了通过作用于这一生化过程来控制牙齿移动程度的可能性。