Morris Shaun K, Brophy Jason, Richardson Susan E, Summerbell Richard, Parkin Patricia C, Jamieson Frances, Limerick Bill, Wiebe Lyle, Ford-Jones E Lee
Hospital for Sick Children, Toronto, Ontario, Canada.
Emerg Infect Dis. 2006 Feb;12(2):274-9. doi: 10.3201/eid1202.050849.
We describe a case of blastomycosis in an 8-year-old boy with Blastomyces-associated osteomyelitis and possible pulmonary involvement. We also identify 309 cases of blastomycosis in Ontario that were seen during a 10-year period, 57% of which occurred from 2001 to 2003. The overall incidence during the study period was 0.30 cases per 100,000 population. Most patients were from north Ontario (n = 188), where the incidence was 2.44 cases per 100,000. The incidence in the Toronto region was 0.29 per 100,000. Thirteen percent of cases occurred in children <19 years of age. These findings substantially increase the number of known cases in Ontario and Canada. Clinicians may encounter persons infected with Blastomyces dermatitidis and must be familiar with its signs and symptoms and be aware of locations, such as northwestern Ontario, where disease is endemic or hyperendemic. We advocate resuming blastomycosis as a reportable disease in Ontario to facilitate tracking cases.
我们描述了一例8岁男孩的芽生菌病，该男孩患有芽生菌相关骨髓炎且可能累及肺部。我们还确定了安大略省在10年期间出现的309例芽生菌病病例，其中57%发生在2001年至2003年期间。研究期间的总体发病率为每10万人0.30例。大多数患者来自安大略省北部（n = 188），那里的发病率为每10万人2.44例。多伦多地区的发病率为每10万人0.29例。13%的病例发生在19岁以下的儿童中。这些发现大幅增加了安大略省和加拿大已知病例的数量。临床医生可能会遇到感染皮炎芽生菌的人，必须熟悉其体征和症状，并了解疾病流行或高度流行的地区，如安大略省西北部。我们主张在安大略省恢复将芽生菌病列为须报告疾病，以便于追踪病例。
