[A mathematical model of the role of Ca2+/calmodulin-dependent protein kinase in the long term increase in effectiveness of synaptic plasticity].

A mathematical model describing initiation and restoring of the long-term potentiation (LTP) is proposed. This model is based on an assumption that Ca2+/Calmodulin-dependent protein kinase from some of second messengers exists in a number of states. The protein kinase ability for securing LTP restoring is connected with autophosphorylation.